Assuming you have installed the "LispWorks with X11 IDE" option, and that you have X11 running and Motif installed, you can use LispWorks with the Motif GUI.
You first must load the Motif GUI into the supplied
lispworks-6-1-0-macos-universal-gtk
image, by
(require "capi-motif")
This loads the necessary module and makes Motif the default library for CAPI.
Then you can start the LispWorks IDE by calling env:start-environment as shown in Start the GTK+ LispWorks GUI. You might want to save an image with the
"capi-motif"
module pre-loaded: do this with a
save-image
script containing
(require "capi-motif")
LispWorks Release Notes and Installation Guide - 23 Dec 2011